Imaging Proliferation of Stage IV Cutaneous Melanoma With 18F-FLT PET/CT
Baseline 18 F-FLT uptake patterns relative to 18 F-FDG, and early changes in 18 F-FLT uptake, were associated with PFS in patients treated with BRAF/MEK inhibitors. These explorative findings suggest that 18 F-FLT PET/CT may have predictive value, warranting confirmation in larger prospective studies.
Authors
- John B.A.G. Haanen (ORCID: https://orcid.org/0000-0001-5884-7704)
- Wouter V. Vogel (ORCID: https://orcid.org/0000-0002-4992-8024)
- Filip De Vos (ORCID: https://orcid.org/0000-0002-9082-5991)
- Else A. Aalbersberg (ORCID: https://orcid.org/0000-0002-4910-3794)
- Marcel P. M. Stokkel (ORCID: https://orcid.org/0000-0002-8131-5690)
- Alfons J.M. van den Eertwegh (ORCID: https://orcid.org/0000-0003-2196-1233)
- Bernies van der Hiel (ORCID: https://orcid.org/0000-0001-8158-405X)
- Carmen A. Vlahu
- Marye J. Boers‐Sonderen (ORCID: https://orcid.org/0009-0005-9624-9189)
Institutions
- Radboud University Nijmegen (NL)
- Radboud University Medical Center (NL)
- The Netherlands Cancer Institute (NL)
- University Medical Center Utrecht (NL)
- Amsterdam University Medical Centers (NL)
- Vrije Universiteit Amsterdam (NL)
- Amsterdam UMC Location Vrije Universiteit Amsterdam (NL)
Publication Details
- Journal
- Clinical Nuclear Medicine
- Published
- 2025-05-27
- DOI
- https://doi.org/10.1097/rlu.0000000000005999
- Primary Topic
- Melanoma and MAPK Pathways
- Type
- article
- Field-Weighted Citation Impact
- 0.00