Postoperative radiotherapy in subtotally resected recurrent WHO grade 1 meningiomas with intermediate-/high-risk molecular profiles
Our findings highlight the combined impact of both the extent of resection and molecular risk profile on prognosis in newly diagnosed cases. While conservative management is feasible in lower-risk primary cases, recurrent or higher-risk patients may benefit from early postoperative RT.
Authors
- Sybren L. N. Maas (ORCID: https://orcid.org/0000-0002-8745-4405)
- Sandro M. Krieg (ORCID: https://orcid.org/0000-0003-4050-1531)
- Eric Y. Stutheit-Zhao (ORCID: https://orcid.org/0000-0003-1277-6335)
- Maximilian Deng (ORCID: https://orcid.org/0000-0003-4925-7600)
- Sebastian Regnery (ORCID: https://orcid.org/0000-0002-6820-884X)
- Katharina Seidensaal (ORCID: https://orcid.org/0000-0001-5969-6426)
- Antje Wick (ORCID: https://orcid.org/0000-0003-0020-6386)
- Stefan M. Pfister (ORCID: https://orcid.org/0000-0002-5447-5322)
- Thomas Held (ORCID: https://orcid.org/0000-0002-3913-4693)
- Laila König (ORCID: https://orcid.org/0000-0001-8402-6694)
- Philipp Sievers (ORCID: https://orcid.org/0000-0003-3237-6021)
- Andreas von Deimling (ORCID: https://orcid.org/0000-0002-5863-540X)
- Lukas Bauer (ORCID: https://orcid.org/0009-0000-7711-934X)
- Felix Sahm (ORCID: https://orcid.org/0000-0001-5441-1962)
- Jonathan W. Lischalk (ORCID: https://orcid.org/0000-0002-3714-7757)
- Klaus K Herfarth (ORCID: https://orcid.org/0000-0002-6325-4193)
- Juliane Hörner‐Rieber (ORCID: https://orcid.org/0000-0003-3911-4438)
- Wolfgang Wick (ORCID: https://orcid.org/0000-0002-6171-634X)
- Christine Jungk (ORCID: https://orcid.org/0009-0004-7911-0268)
- Tanja Eichkorn (ORCID: https://orcid.org/0000-0003-0150-1328)
- Philipp Hoegen-Saßmannshausen
- Inga Jessen
- Sophie Rauh
- Jürgen Debus
- Günes Anil
Institutions
- University Health Network (CA)
- German Cancer Research Center (DE)
- Heidelberg University (DE)
- Leiden University Medical Center (NL)
- University Hospital Heidelberg (DE)
- Princess Margaret Cancer Centre (CA)
- NYU Langone Health (US)
- Düsseldorf University Hospital (DE)
- Heidelberger Institut für Radioonkologie (DE)
- National Center for Tumor Diseases (DE)
- Hopp Children's Cancer Center Heidelberg (DE)
- Erasmus MC Cancer Institute (NL)
- Heinrich Heine University Düsseldorf (DE)
Publication Details
- Journal
- Neuro-Oncology
- Published
- 2025-05-27
- DOI
- https://doi.org/10.1093/neuonc/noaf125
- Citations
- 1
- Primary Topic
- Meningioma and schwannoma management
- Type
- article
- Field-Weighted Citation Impact
- 1.35