Antifungal activity and mechanism of novel peptide <i>Glycine max</i> antimicrobial peptide (GmAMP) against fluconazole-resistant <i>Candida tropicalis</i>.
GmAMP can disrupt the cell membrane of fluconazole-resistant <i>C. tropicalis</i> and also shows favorable safety and therapeutic efficacy <i>in vivo</i>. Accordingly, GmAMP has the potential to be an agent against drug-resistant fungi.
Authors
- Guo Guo (ORCID: https://orcid.org/0000-0002-2866-7080)
- Zhenlong Jiao (ORCID: https://orcid.org/0000-0001-8080-2887)
- Chaoqin Sun
- Jian Peng (ORCID: https://orcid.org/0000-0003-3047-1455)
- Jin Zhang (ORCID: https://orcid.org/0000-0003-3074-5647)
- Na Zhao
- Ruxia Cai
- Mingjiao Huang
Institutions
- Guiyang Medical University (CN)
Publication Details
- Journal
- PubMed
- Published
- 2025-01-01
- DOI
- https://doi.org/10.7717/peerj.19372
- Primary Topic
- Antimicrobial Peptides and Activities
- Type
- article
- Field-Weighted Citation Impact
- 0.00