[<i>Tiaozhou Ziyin</i> recipe for treatment of premature ovarian insufficiency: efficacy, safety and mechanism].
The therapeutic mechanism of TZZY recipe for POI involves multiple active ingredients, multiple therapeutic targets and multiple pathways, and activating the PI3K /Akt pathway is one of its main mechanisms of action, to improve ovarian reserve function, alleviate clinical symptoms, and enhance clinical efficacy in POI patients.
Authors
- Xiaowei Nie (ORCID: https://orcid.org/0000-0003-2443-0569)
- Peipei Tang
- Wenting Zuo (ORCID: https://orcid.org/0009-0000-1521-1861)
- Yanyun Yin (ORCID: https://orcid.org/0000-0003-4870-9281)
- Yuling Li (ORCID: https://orcid.org/0000-0003-0631-2884)
- Jingyu Huang (ORCID: https://orcid.org/0000-0001-9591-9981)
- Yong Tan (ORCID: https://orcid.org/0000-0001-7494-5689)
Institutions
- Nanjing University of Chinese Medicine (CN)
Publication Details
- Journal
- PubMed
- Published
- 2025-05-20
- DOI
- https://doi.org/10.12122/j.issn.1673-4254.2025.05.05
- Primary Topic
- Ginseng Biological Effects and Applications
- Type
- article