MFAP4 as a novel biomarker for predicting liver fibrosis and prognosis in infants with biliary atresia through the integration of bioinformatics with clinical data analysis

We discovered that MFAP4 is a crucial BA-associated gene, and validated its expression in BA. Furthermore, serum MFAP4 levels may serve as predictive markers for the degree of liver fibrosis and autologous liver survival after Kasai surgery.

Authors

Institutions

Publication Details

Journal
Frontiers in Pediatrics
Published
2025-05-26
DOI
https://doi.org/10.3389/fped.2025.1611564
Citations
1
Primary Topic
Pediatric Hepatobiliary Diseases and Treatments
Type
article
Field-Weighted Citation Impact
2.01
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

MFAP4 as a novel biomarker for predicting liver fibrosis and prognosis in infants with biliary atresia through the integration of bioinformatics with clinical data analysis

Jianghua Zhan, Chunxiao Yang
1 citations
Frontiers in Pediatrics
Pediatric Hepatobiliary Diseases and Treatments
2.01
article

MFAP4 as a novel biomarker for predicting liver fibrosis and prognosis in infants with biliary atresia through the integration of bioinformatics with clinical data analysis

Jianghua Zhan, Chunxiao Yang
article en
1 citations

Abstract

We discovered that MFAP4 is a crucial BA-associated gene, and validated its expression in BA. Furthermore, serum MFAP4 levels may serve as predictive markers for the degree of liver fibrosis and autologous liver survival after Kasai surgery.

Frontiers in PediatricsVol. 13
Tianjin Children's Hospital (CN), Central Hospital of Zibo (CN), Tianjin Medical University (CN)
Openalex Percentile: Top 15%
Pediatric Hepatobiliary Diseases and Treatments
2.01
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.