Effectiveness, safety, and practicality of intramuscular progesterone in restoring pregnancy outcomes during frozen embryo transfers
Intramuscular P4 effectively increased serum P4 levels resulting in pregnancy and neonatal outcomes comparable to those in patients with P4 levels ≥10 ng/ml. This approach provides a safe, effective intervention to improve FET outcomes, supporting the routine inclusion of serum P4 testing and intramuscular P4 rescue in standard FET protocols.
Authors
- Tran Hue Tran
- Therese Vu (ORCID: https://orcid.org/0000-0003-2831-2957)
- Ly T. T. Nguyen (ORCID: https://orcid.org/0000-0001-9372-9690)
- Chien Ngoc Nguyen (ORCID: https://orcid.org/0000-0002-1555-9320)
- Van Thi Cam Nguyen
- Robert J. Norman (ORCID: https://orcid.org/0000-0002-3118-3896)
- Nha Ba Pham
- Yen Nguyen (ORCID: https://orcid.org/0000-0002-0764-4795)
- L.T. Le
- Xuyen Thi Nguyen
- Xuan-Hung Nguyen
- Thuy Thi Thu Nguyen (ORCID: https://orcid.org/0000-0001-7239-8458)
- Huong To
- Thanh T. Le (ORCID: https://orcid.org/0000-0002-7756-9479)
- Phuong Bich Vu
- Quynh Thi Nguyen (ORCID: https://orcid.org/0000-0003-0207-5690)
- Trang Thi Nhu Nguyen
- Yen Pham
Institutions
- Vinmec Times City International Hospital (VN)
- VinUniversity (VN)
- The University of Adelaide (AU)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2025-05-26
- DOI
- https://doi.org/10.3389/fendo.2025.1592956
- Citations
- 3
- Primary Topic
- Reproductive Biology and Fertility
- Type
- article
- Field-Weighted Citation Impact
- 5.64