A telomere-associated molecular landscape reveals immunological, microbial, and therapeutic heterogeneity in colorectal cancer
TELscore is a robust stratification tool that captures the interplay between tumor biology, immune characteristics, and microbial ecology in colorectal cancer. By identifying clinically relevant subtypes with distinct therapeutic vulnerabilities, TELscore offers a powerful framework to advance personalized treatment and precision oncology.
Authors
- Yinmeng Zhang (ORCID: https://orcid.org/0009-0001-9486-2466)
- Jiahui Zhao (ORCID: https://orcid.org/0009-0006-4620-7738)
- Jiawei Fan (ORCID: https://orcid.org/0009-0007-4559-4657)
- Yan Xia (ORCID: https://orcid.org/0000-0003-4509-0137)
- Hong Xu (ORCID: https://orcid.org/0000-0003-1228-3645)
- He Zhu
Institutions
- Jilin University (CN)
- First Hospital of Jilin University (CN)
Publication Details
- Journal
- Frontiers in Molecular Biosciences
- Published
- 2025-05-26
- DOI
- https://doi.org/10.3389/fmolb.2025.1615533
- Citations
- 3
- Primary Topic
- Cancer Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 3.70