Enhancing tofacitinib’s therapeutic efficacy in murine arthritis with a synbiotic formulation comprising Bacillus megaterium DSM 32963 and an Omega-3 fatty acid lysine salt
In conclusion, the specific synbiotic formulation shows promise as a complementary nutritional therapy for RA, improving disease outcomes and modulating immune responses.
Authors
- Annette Zehrer
- Alexandra Rausch (ORCID: https://orcid.org/0009-0005-0629-0867)
- Paul M. Jordan (ORCID: https://orcid.org/0000-0002-8364-4236)
- Oliver Werz (ORCID: https://orcid.org/0000-0002-5064-4379)
- Heike tom Dieck (ORCID: https://orcid.org/0000-0002-3412-1180)
- Thomas Berngruber
Institutions
- Evonik (Germany) (DE)
- German Red Cross (DE)
- Weber and Weber (Germany) (DE)
- Friedrich Schiller University Jena (DE)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-05-26
- DOI
- https://doi.org/10.3389/fimmu.2025.1540878
- Primary Topic
- Pharmacological Effects of Natural Compounds
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Evonik Operations