Biopolymers in Floating Drug Delivery Systems

Abstract: Floating drug delivery systems are significant for gastric retention characteristics and improving the absorption and bioavailability of drugs. Several polymers have been used in such systems as drug carriers. Biopolymers, including alginate, chitosan, guar gum, and gelatin obtained from plant or animal sources have also been applied in such systems. Such biopolymers are biocompatible and biodegradable and provide suitable characteristics for swelling and hydrogel formation. The present review summarizes several biopolymers used in floating drug delivery including their sources, structure, and recent research studies for gastric retention.