UPLC-Q-TOF-MS based investigation into the bioactive compounds and molecular mechanisms of Qishen Huanwu capsule attenuates anthracycline-induced cardiotoxicity

QSHWC alleviates anthracycline-induced cardiotoxicity by targeting cardiac pyroptosis through the PI3K/AKT pathway, while providing a multi-target therapeutic strategy.

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Publication Details

Journal
Phytomedicine
Published
2025-05-26
DOI
https://doi.org/10.1016/j.phymed.2025.156877
Citations
2
Primary Topic
Chemotherapy-induced cardiotoxicity and mitigation
Type
article
Field-Weighted Citation Impact
2.78
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article

UPLC-Q-TOF-MS based investigation into the bioactive compounds and molecular mechanisms of Qishen Huanwu capsule attenuates anthracycline-induced cardiotoxicity

Honggui Liu, Na Zhao, Feng Wang, Jin‐Meng Lv et al.
2 citations
Phytomedicine
Chemotherapy-induced cardiotoxicity and mitigation
2.78
article

UPLC-Q-TOF-MS based investigation into the bioactive compounds and molecular mechanisms of Qishen Huanwu capsule attenuates anthracycline-induced cardiotoxicity

Honggui Liu, Na Zhao, Feng Wang, Jin‐Meng Lv, Lixin Wang, Jing Yang, Jingjing Dong, Gui Yin, Nana Feng
article en
2 citations

Abstract

QSHWC alleviates anthracycline-induced cardiotoxicity by targeting cardiac pyroptosis through the PI3K/AKT pathway, while providing a multi-target therapeutic strategy.

PhytomedicineVol. 143
Cangzhou Central Hospital (CN), Integrated Chinese Medicine (China) (HK), People's Hospital of Cangzhou (CN)
Openalex Percentile: Top 10%
Chemotherapy-induced cardiotoxicity and mitigation
2.78
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