Streptococcus pneumoniae carriage, antimicrobial resistance, and serotype distribution in children and adults from Paraguay in the post-vaccinal era
Our findings reveal worrying trends in the epidemiology of <i>S. pneumoniae</i> in Paraguay, including the persistence of vaccine-type serotypes among vaccinated children and an increasing resistance to antibiotics of isolated strains. Given the critical role of carriage studies in monitoring the impact of PCV in LMICs, the public health community should explore ways to improve their feasibility and cost-effectiveness and better integrate these efforts into routine vaccine preventable disease surveillance systems.
Authors
- Mélina Messaoudi (ORCID: https://orcid.org/0000-0002-7049-7206)
- Graciela Russomando
- Sonia Abente (ORCID: https://orcid.org/0000-0002-0263-4205)
- Florence Komurian-Pradel (ORCID: https://orcid.org/0000-0002-1023-0796)
- Milen Milenkov
- Valentina Picot
- Sélilah Amour (ORCID: https://orcid.org/0000-0002-4804-7209)
- Rosa Guillén (ORCID: https://orcid.org/0000-0002-4778-4960)
- Norma Fariña (ORCID: https://orcid.org/0000-0002-8816-1786)
- Ines Hahn (ORCID: https://orcid.org/0000-0001-7703-8160)
- Monserrat Aldama
- Lorena Grau
- Zunilda Sánchez
- Héctor Castro
Institutions
- Université Claude Bernard Lyon 1 (FR)
- École Normale Supérieure de Lyon (FR)
- Centre National de la Recherche Scientifique (FR)
- Inserm (FR)
- Instituto de Investigaciones en Ciencias de la Salud (AR)
- Hospices Civils de Lyon (FR)
- Fondation Mérieux (FR)
- Guyra Paraguay (PY)
- Ministerio de Salud (NI)
- Ministerio de Salud Pública y Bienestar Social (PY)
- Centre International de Recherche en Infectiologie (FR)
- Universidad Nacional de Asunción (PY)
Publication Details
- Journal
- Frontiers in Public Health
- Published
- 2025-05-26
- DOI
- https://doi.org/10.3389/fpubh.2025.1584857
- Citations
- 3
- Primary Topic
- Pneumonia and Respiratory Infections
- Type
- article
- Field-Weighted Citation Impact
- 4.06
Funders
- Universidad Nacional de Asunción
- Fondation Mérieux