Stage-specific transcriptomic analysis reveals insights into the development, reproduction and biological function of allergens in the European house dust mite Dermatophagoides pteronyssinus
This study provides the first genome-wide transcriptomic analysis of a HDM across life stages and sexes, expanding our understanding of the molecular mechanisms underlying mite development, sexual reproduction, and allergen expression. The generated data, fully available via supplementary spreadsheet and the ORCAE online platform, provide a valuable foundation for future allergy research and the development of new mite control strategies.
Authors
- José Cristian Vidal‐Quist (ORCID: https://orcid.org/0000-0002-3931-2592)
- Pedro Hernández‐Crespo (ORCID: https://orcid.org/0000-0001-9350-3640)
- Bart N. Lambrecht (ORCID: https://orcid.org/0000-0003-4376-6834)
- Félix Ortego (ORCID: https://orcid.org/0000-0002-7778-8508)
- Stéphane Rombauts (ORCID: https://orcid.org/0000-0002-3985-4981)
Institutions
- Ghent University Hospital (BE)
- Ghent University (BE)
- VIB-UGent Center for Plant Systems Biology (BE)
- VIB-UGent Center for Inflammation Research (BE)
- Centro de Investigaciones Biológicas Margarita Salas (ES)
Publication Details
- Journal
- BMC Genomics
- Published
- 2025-05-26
- DOI
- https://doi.org/10.1186/s12864-025-11703-w
- Primary Topic
- Allergic Rhinitis and Sensitization
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Fonds Wetenschappelijk Onderzoek