Performance of A Statistical-Based Automatic Contrast-to-Noise Ratio Measurement on Images of the ACR CT Phantom

This study evaluates the performance of a statistical-based automatic contrast-to-noise ratio (CNR) measurement method on images of the ACR CT phantom under varying imaging parameters. A statistical automatic method for segmenting low-contrast objects and for measuring CNR was recently introduced. The method employs a 25 mm region of interest (ROI), rotated in 2° clockwise steps, to identify the low-contrast object by locating the maximum CT value. The CNR was measured on images acquired with different parameters: tube voltage (80-140 kVp), tube current (80-200 mA), slice thickness (1.25-10 mm), field of view (190-230 mm), and convolution kernel (edge, ultra, lung, bone, chest, standard). The automatic results were compared to manual measurements. The automatic method accurately identified the largest low-contrast object. The CNR values from the automatic and manual methods showed no significant difference (<i>p</i> > 0.05). The CNR increased with higher tube voltage and current, and with thinner slice thickness. Chest and standard kernels yielded higher CNRs, while edge, ultra, lung, and bone kernels yielded lower ones. The CNR remained stable with minor FOV changes. The statistical-based automatic method provided accurate and consistent CNR measurements across a range of imaging settings for the ACR CT phantom.