The Relationship between Fatigue and Quality of Life in Cancer Patients Undergoing Chemotherapy

Background: Fatigue is one of the most common side effects experienced by cancer patients undergoing chemotherapy, which can negatively impact their quality of life. This study aims to analyze the relationship between fatigue levels and quality of life in cancer patients undergoing chemotherapy. Methods: This study employed a cross-sectional design with a total sample of 300 cancer patients undergoing chemotherapy at a referral hospital. The sampling method used was purposive sampling. Fatigue was measured using the Fatigue Severity Scale (FSS), while quality of life was assessed using the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30). Data analysis was conducted using Pearson correlation tests. Results: The study found that the majority of patients experienced moderate to severe fatigue (M = 5.8; SD = 1.3). A significant negative correlation was found between fatigue and quality of life (r = -0.65, p < 0.001), indicating that higher levels of fatigue were associated with lower quality of life. Conclusion: Fatigue has a significant impact on reducing the quality of life of cancer patients undergoing chemotherapy. Effective nursing interventions to manage fatigue are necessary to improve patients’ quality of life.