Pagets Disease of the Breast

Background: Paget’s disease of the breast also called mammary Paget’s disease [MPD] was first described by Sir James Paget an English surgeon and a medical pioneer in the 19th century in 1874. In his report, fifteen women with a chronic eczematous disease on the skin of the nipple and the areola also had an associated intra ductal carcinoma of the underlying mammary gland. It is a rare type of cancer that develops in the skin of the nipple, and sometimes the areola, for this reason patients tend to take it less seriously. Conclusion: The treatment for Paget’s disease of the breast typically involves surgery, usually a mastectomy or breast conserving surgery with radiation, and effective chemotherapy or hormone therapy, depending on the underlying cancer’s characteristics.

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Publication Details

Journal
Advances in Breast Cancer Research
Published
2025-01-01
DOI
https://doi.org/10.4236/abcr.2025.143005
Primary Topic
Cancer and Skin Lesions
Type
article
Field-Weighted Citation Impact
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article

Pagets Disease of the Breast

Onyeyirichi Otuu, Chika O. Duru, Nneka Alice Sunday-Nweke, Moses I. Ekuma et al.
Advances in Breast Cancer Research
Cancer and Skin Lesions
article

Pagets Disease of the Breast

Onyeyirichi Otuu, Chika O. Duru, Nneka Alice Sunday-Nweke, Moses I. Ekuma, Ozoemena S. Oboke, Udu Chijioke Udu, Somadina Ikpeze, Kenneth A. Omoruyi, Samuel U. Okparaoka
article en

Abstract

Background: Paget’s disease of the breast also called mammary Paget’s disease [MPD] was first described by Sir James Paget an English surgeon and a medical pioneer in the 19th century in 1874. In his report, fifteen women with a chronic eczematous disease on the skin of the nipple and the areola also had an associated intra ductal carcinoma of the underlying mammary gland. It is a rare type of cancer that develops in the skin of the nipple, and sometimes the areola, for this reason patients tend to take it less seriously. Conclusion: The treatment for Paget’s disease of the breast typically involves surgery, usually a mastectomy or breast conserving surgery with radiation, and effective chemotherapy or hormone therapy, depending on the underlying cancer’s characteristics.

Advances in Breast Cancer ResearchVol. 14(03)
Openalex Percentile: Top 78%
Cancer and Skin Lesions
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