Central Nervous System Pseudomass in NeuroBehçet's Syndrome: A Rare Radiological Manifestation and Diagnostic Challenge

Neuro-Behçet's Syndrome (NBS) is a rare yet potentially severe neurological manifestation of Behçet's disease (BD). Although the condition frequently affects the brainstem, basal ganglia, and diencephalon, [1,2] its occurrence as a mass-like lesion (pseudotumor) is exceedingly uncommon. These tumefactive lesions can resemble neoplastic, infectious, or demyelinating conditions, which often hinders prompt diagnosis and treatment. [1-3] In this report, we discuss a 56-year-old female from Libya with a history of Behçet’s disease, who presented with headaches, visual disturbances, and cognitive slowing. Magnetic Resonance Imaging (MRI) findings indicated a high T2/FLAIR signal in the bilateral basal ganglia and the left cerebellar hemisphere, extending into the middle cerebellar peduncle, accompanied by faint contrast enhancement.