Electroacupuncture exerts antipruritic and anti-inflammatory effects on atopic dermatitis by activating CB2 receptor
EA exerts therapeutic effects on persistent itch and skin inflammation in AD mice by activating CB2R, thereby inhibiting mast cell and CD4<sup>+</sup> T cell proliferation and the expression of associated inflammatory factors, as well as downstream ERK phosphorylation.
Authors
- Wenqiang Ge (ORCID: https://orcid.org/0000-0003-3467-3361)
- Xiang‐Hong Jing (ORCID: https://orcid.org/0000-0003-0272-1576)
- Xuefei Hu (ORCID: https://orcid.org/0000-0002-1840-7787)
- Ouyang Zhanmu (ORCID: https://orcid.org/0000-0002-4173-1868)
- Xin Liu (ORCID: https://orcid.org/0000-0001-8542-2963)
- Man Li (ORCID: https://orcid.org/0000-0003-4041-0437)
- Shiying Lin (ORCID: https://orcid.org/0000-0002-9819-9059)
- Hongxiang Chen (ORCID: https://orcid.org/0000-0003-0989-3565)
- Yanzhen Li (ORCID: https://orcid.org/0000-0002-7528-7996)
- Qing Tian (ORCID: https://orcid.org/0000-0002-2183-2012)
- Yang Yang (ORCID: https://orcid.org/0000-0002-3362-7155)
- Peiling Li (ORCID: https://orcid.org/0009-0007-2906-5130)
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Wuhan Union Hospital (CN)
- China Academy of Chinese Medical Sciences (CN)
- China Association of Acupuncture-Moxibustion (CN)
- Union Hospital (CN)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- Chinese Medicine
- Published
- 2025-05-26
- DOI
- https://doi.org/10.1186/s13020-025-01102-4
- Citations
- 1
- Primary Topic
- Dermatology and Skin Diseases
- Type
- article
- Field-Weighted Citation Impact
- 2.00
Funders
- National Natural Science Foundation of China
- China Postdoctoral Science Foundation
- Huazhong University of Science and Technology
- Shenzhen Fundamental Research Program
- Shenzhen Knowledge Innovation Program
- Fundamental Research Funds for Central Universities of the Central South University