Docosahexaenoic acid protects against alcohol‐induced constriction of cerebral arteries and inhibition of vascular smooth muscle <scp>BK</scp> channels
DHA protects against alcohol-induced cerebral artery constriction and BK channel inhibition in a sexually dimorphic manner via cellular mechanisms in vascular myocytes. This action of DHA is independent of changes in BK subunit membrane levels and of a previously identified fatty acid-sensing site in the BK channel.
Authors
- Elizabeth A. Tolley (ORCID: https://orcid.org/0000-0002-6820-817X)
- Anna N. Bukiya (ORCID: https://orcid.org/0000-0003-0655-2319)
- Steven Mysiewicz
- Alex M. Dopico (ORCID: https://orcid.org/0000-0003-4210-0096)
- Sydney Hawks
- Shiwani Thapa (ORCID: https://orcid.org/0009-0007-9249-4317)
- Ricardo Morales (ORCID: https://orcid.org/0000-0001-6272-570X)
Institutions
- University of Tennessee Health Science Center (US)
Publication Details
- Journal
- Alcohol Clinical and Experimental Research
- Published
- 2025-05-26
- DOI
- https://doi.org/10.1111/acer.70073
- Primary Topic
- Fatty Acid Research and Health
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institute on Alcohol Abuse and Alcoholism
- NIH Office of the Director