Effects of maternal isolated oligohydramnios on blood metabolic profile in term neonates: a retrospective observational study

The difference in the blood metabolomics profiles between neonates with maternal IO and HC was mainly in the pathway of Phe, Tyr and Trp biosynthesis. Phe, Tyr, and Trp biosynthesis may be involved in the physiological processes related to the nervous system and digestive system. Continuous attention to changes in blood metabolites in IO neonates and the effect on body growth and development is necessary.

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Publication Details

Journal
BMC Pregnancy and Childbirth
Published
2025-05-26
DOI
https://doi.org/10.1186/s12884-025-07729-3
Primary Topic
Birth, Development, and Health
Type
article
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article

Effects of maternal isolated oligohydramnios on blood metabolic profile in term neonates: a retrospective observational study

Guiying Zhuang, Jie Song, Qiuping Yang, Zhirong Deng et al.
BMC Pregnancy and Childbirth
Birth, Development, and Health
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Effects of maternal isolated oligohydramnios on blood metabolic profile in term neonates: a retrospective observational study

Guiying Zhuang, Jie Song, Qiuping Yang, Zhirong Deng, Li Zhou, Jie Li, Congcong Shi, Yao Cai, Ximei Yang, Bingqing Liu, Guixian Pan
article en

Abstract

The difference in the blood metabolomics profiles between neonates with maternal IO and HC was mainly in the pathway of Phe, Tyr and Trp biosynthesis. Phe, Tyr, and Trp biosynthesis may be involved in the physiological processes related to the nervous system and digestive system. Continuous attention to changes in blood metabolites in IO neonates and the effect on body growth and development is necessary.

BMC Pregnancy and ChildbirthVol. 25(1)
Sun Yat-sen University (CN), Sixth Affiliated Hospital of Sun Yat-sen University (CN), Guangdong Province Women and Children Hospital (CN)
Zero hunger
Openalex Percentile: Top 84%
Birth, Development, and Health
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