Predictive modelling of mandibular osteoradionecrosis in head and neck cancer patients: clinical and dosimetric insights
V50 and post-RT dental extractions are key predictors of ORN. The developed nomogram enables personalized risk assessment, supporting treatment optimization. These findings emphasize the need for tailored RT planning and dental care to mitigate ORN risk, warranting validation in multi-institutional cohorts.
Authors
- Ali Modabber
- Michael J. Eble (ORCID: https://orcid.org/0000-0001-8540-5119)
- Ahmed Allam Mohamed (ORCID: https://orcid.org/0000-0002-0978-1996)
- Frank Hölzle (ORCID: https://orcid.org/0000-0002-2298-3517)
- Julian Leeder
Institutions
- Integrated Oncology (United States) (US)
- RWTH Aachen University (DE)
Publication Details
- Journal
- Clinical Oral Investigations
- Published
- 2025-05-26
- DOI
- https://doi.org/10.1007/s00784-025-06385-3
- Citations
- 2
- Primary Topic
- Oral health in cancer treatment
- Type
- article
- Field-Weighted Citation Impact
- 3.04