Elevated level of circulating VEGF in Chinese patients with hereditary angioedema and its correlation with disease status
Circulating VEGF level elevated in patients with HAE during attack-free periods, particularly among those with greater disease burden, suggesting the involvement of vascular endothelial dysfunction in the pathogenesis of HAE. VEGF may serve as a predictive biomarker for risk stratification and disease monitoring in HAE.
Authors
- Ruoyu Ji (ORCID: https://orcid.org/0000-0001-6507-0702)
- Yuxiang Zhi (ORCID: https://orcid.org/0000-0001-7539-6650)
- Yijing Xu
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking Union Medical College Hospital (CN)
Publication Details
- Journal
- Orphanet Journal of Rare Diseases
- Published
- 2025-05-26
- DOI
- https://doi.org/10.1186/s13023-025-03776-3
- Citations
- 1
- Primary Topic
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Type
- article
- Field-Weighted Citation Impact
- 1.63
Funders
- Peking Union Medical College Hospital