Changes in the main epidemiological indicators of type 1 diabetes mellitus in the children’s population of the Luhansk People’s Republic in 2010-2021

BACKGROUND: The progression of incidence and prevalence of type 1 DM among children worldwide is undeniable and is a priority problem for healthcare systems of all countries. AIM: assessment of changes in the main epidemiological data on type 1 diabetes mellitus (DM1) in children living in the territory of the Luhansk People’s Republic (LPR) over the past 10 years. MATERIALS AND METHODS: assessment of the dynamics of regional epidemiological indicators (incidence, prevalence and mortality) in type 1 diabetes in children and adolescents over the time period from 2010 to 2021. The data were studied on the basis of the cardio rheumatology department with endocrinological beds of the Luhansk Republican Children’s Clinical Hospital of the LPR by colleagues of the Department of Pediatrics of Additional Professional Education and Propaedeutic of Pediatrics of the Luhansk St. Luke State Medical University of the Ministry of Health of the Russian Federation. The object of the study was the database of the regional register of the state statistics service. RESULTS: the final total quantitative indicator of children and adolescents with DM 1 as of 01.01.2023 was 328 people, of which 130 girls (39.7%) and 104 boys (31.7%) entered the first age group (0-14 years), in the second statistical age group (15–17 years) there were 42 girls (12.8%) and 52 boys (15.8%). In just ten years, the prevalence of DM 1 increased by 1.7 times in the first age group, and in the second, the increase was 1.2 times. Morbidity rates increased 1.6 times in both age groups over the same period. CONCLUSION : the analysis of the results of the study indicates that a protracted armed conflict has a negative impact as a significant stress factor on the development, prolongation, and decrease in the control of type 1 diabetes mellitus in children and adolescents.