The relationship of methylation and mRNA expression profile of AUTS2 with suicidal ideation in adolescents with bipolar depression

The elevated methylation level of CpG14.15.16 of the AUTS2 gene might be involved in the pathophysiology of suicide ideation in adolescents with bipolar depression, which might be mediated by the mRNA expression of AUTS2.

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Publication Details

Journal
BMC Psychiatry
Published
2025-05-26
DOI
https://doi.org/10.1186/s12888-025-06927-9
Primary Topic
Bipolar Disorder and Treatment
Type
article
Field-Weighted Citation Impact
0.00

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article

The relationship of methylation and mRNA expression profile of AUTS2 with suicidal ideation in adolescents with bipolar depression

Shaohong Zou, Xiaoqin Shen, C. Wang, Lu Liu et al.
BMC Psychiatry
Bipolar Disorder and Treatment
article

The relationship of methylation and mRNA expression profile of AUTS2 with suicidal ideation in adolescents with bipolar depression

Shaohong Zou, Xiaoqin Shen, C. Wang, Lu Liu, Cheng Zhang, Alimire Alimujiang
article en

Abstract

The elevated methylation level of CpG14.15.16 of the AUTS2 gene might be involved in the pathophysiology of suicide ideation in adolescents with bipolar depression, which might be mediated by the mRNA expression of AUTS2.

BMC PsychiatryVol. 25(1)
Xinjiang Medical University (CN)
Natural Science Foundation of Xinjiang Province, Natural Science Foundation of Xinjiang
Openalex Percentile: Top 86%
Bipolar Disorder and Treatment
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