Impact of thymoquinone on the Nrf2/HO-1 and MAPK/NF-κB axis in mitigating 5-fluorouracil-induced acute kidney injury in vivo

Based on the results obtained in the present study, TQ appears to be a beneficial agent that could be used as an adjuvant therapy for the prevention of 5-FU-induced nephrotoxicity.

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Publication Details

Journal
Frontiers in Oncology
Published
2025-05-26
DOI
https://doi.org/10.3389/fonc.2025.1572095
Citations
1
Primary Topic
Nigella sativa pharmacological applications
Type
article
Field-Weighted Citation Impact
2.38

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article

Impact of thymoquinone on the Nrf2/HO-1 and MAPK/NF-κB axis in mitigating 5-fluorouracil-induced acute kidney injury in vivo

Summya Rashid
1 citations
Frontiers in Oncology
Nigella sativa pharmacological applications
2.38
article

Impact of thymoquinone on the Nrf2/HO-1 and MAPK/NF-κB axis in mitigating 5-fluorouracil-induced acute kidney injury in vivo

Summya Rashid
article en
1 citations

Abstract

Based on the results obtained in the present study, TQ appears to be a beneficial agent that could be used as an adjuvant therapy for the prevention of 5-FU-induced nephrotoxicity.

Frontiers in OncologyVol. 15
Prince Sattam Bin Abdulaziz University (SA)
Prince Sattam bin Abdulaziz University
Openalex Percentile: Top 13%
Nigella sativa pharmacological applications
2.38
DOIOpen Access PDFOpenAlex
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Impact of thymoquinone on the Nrf2/HO-1 and MAPK/NF-κB axis in mitigating 5-fluorouracil-induced acute kidney injury in vivo — Summya Rashid · Frontiers in Oncology (2025) | TGRS Research Map | TGRS