Research Progress on the Relationship between Time within the Target Range of Glucose and Diabetes-Related Complications

随着持续血糖监测(Continue Glucose Monitoring, CGM)技术的广泛应用，葡萄糖目标范围内时间(Time in Range, TIR)成为评估糖尿病患者血糖控制水平的重要指标。TIR反映糖尿病患者的平均血糖水平和血糖波动等控制情况，与糖尿病并发症发生发展密切相关，对于糖尿病并发症的预防、早期发现和干预具有重要意义。本文就近年来关于TIR与糖尿病相关并发症的研究进展进行综述，以期为糖尿病并发症的临床管理提供新视角和理论依据。Time in range (TIR) of glucose has become an important indicator for evaluating the blood glucose control level of diabetic patients, with the wide application of continuous glucose monitoring (CGM) technology. TIR not only reflects the average blood glucose level of patients but also reveals the fluctuation of blood glucose, which is of great significance for the prevention, early detection and intervention of diabetic complications. This article reviews the recent research progress on TIR and its association with diabetes-related complications, aiming to provide new perspectives and a theoretical basis for the clinical management of diabetes-related complications.