Progress of Research on Correlation between <i>Helic</i><i>obacter pylori</i> and Colorectal Neoplasms

幽门螺杆菌(Helicobacter pylori, Hp)是一种全球性病原体，其致病机制与人类肿瘤发生发展的相关性持续受到学界关注。近年来大量研究证实，Hp感染除与胃癌有明确因果关系外，其与结直肠肿瘤的发病风险存在显著关联，特别是相关机制研究已成为当前消化系统肿瘤领域的热点。本文通过探讨两者之间的概念、流行病学、相关性、致病机制及治疗作一全面综述，期望能够增强大众对这两种疾病的认识，并为其预防与治疗提供有益的参考和见解。Helicobacter pylori (Hp) is a global pathogen, and the correlation between its pathogenic mechanism and the development of human tumors continues to attract academic attention. In recent years, a large number of studies have confirmed that Hp infection has a clear causal relationship with gastric cancer, and it is significantly associated with the risk of colorectal neoplasms, especially the related mechanism research has become a hot spot in the field of digestive system tumors. By discussing the concept, epidemiology, correlation, pathogenesis and treatment of the two diseases, this paper makes a comprehensive review, hoping to enhance the public’s understanding of the two diseases and provide useful reference and insight for their prevention and treatment.