Research Progress on Diagnostic Methods for Invasive Pulmonary Fungal Infections

侵袭性肺真菌感染是临床上常见的感染性疾病，引起侵袭性肺真菌感染常见病原体包括曲霉菌、念珠菌、隐球菌、肺孢子菌等。近年来，因糖皮质激素、免疫抑制剂及化疗药的使用和人口老龄化，免疫功能受损人群增多，侵袭性肺真菌感染发病率也呈上升趋势，且治疗费用和死亡率均较高。侵袭性肺真菌感染缺乏特异性临床表现，诊断方法存在局限，常因漏诊或误诊而延误治疗时间，故准确诊断至关重要。本文对目前侵袭性肺真菌感染诊断方法研究进展进行介绍和评价，从而提高临床上诊断侵袭性肺真菌感染的水平。Invasive pulmonary fungal infection is a common infectious disease in clinical practice, common pathogens causing invasive pulmonary fungal infection include Aspergillus, Candida, Cryptococcus, Pneumocystis jiroveci, etc. In recent years, due to the use of glucocorticoids, immunosuppressants and chemotherapy drugs and the aging of the population, the number of people with compromised immune function has increased. The incidence of invasive pulmonary fungal infections is also on the rise, and treatment costs and mortality are high. Invasive pulmonary fungal infections lack specific clinical manifestations and diagnostic methods are limited. Treatment is often delayed due to missed or misdiagnosed cases, so accurate diagnosis is crucial. This article introduces and evaluates the current research progress in diagnostic methods for invasive pulmonary fungal infections, thereby improving the clinical diagnosis of invasive pulmonary fungal infections.