Efficacy of Ferrous Sulphate in the Management of Iron Deficiency Anemia in Children

Background Iron deficiency anemia (IDA) is a highly prevalent disorder among the pediatric population and has a significant impact on growth and health. Ferrous sulfate is commonly prescribed for the treatment of IDA; however, its efficacy in the pediatric population requires further research. Objective This study aimed to evaluate the efficacy of ferrous sulfate in improving hemoglobin (Hb) and ferritin levels in children diagnosed with IDA. Methods A quasi-experimental study was conducted involving 108 participants aged 1-8 years who were diagnosed with IDA. Participants received ferrous sulfate supplements for three months. Hemoglobin and serum ferritin levels were measured both at baseline and after three months of treatment. Results Ferrous sulfate administration resulted in a significant increase in hemoglobin levels by an average of 3.11 mg/dl and a net increase in ferritin levels by 5.9 ng/ml after 3 months of treatment. Additionally, a positive association was found between low Hb levels and underweight children<i>.</i> Conclusion Ferrous sulfate is an effective therapeutic agent for managing IDA in children, leading to significant improvements in hemoglobin and ferritin levels. Further research involving RCTs with longer follow-up periods is recommended.

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Publication Details

Journal
Cureus
Published
2025-05-26
DOI
https://doi.org/10.7759/cureus.84826
Primary Topic
Iron Metabolism and Disorders
Type
article
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article

Efficacy of Ferrous Sulphate in the Management of Iron Deficiency Anemia in Children

Farhat Naz, Fahad Shafiq, Tahir Hassan, Asifur Rahman et al.
Cureus
Iron Metabolism and Disorders
article

Efficacy of Ferrous Sulphate in the Management of Iron Deficiency Anemia in Children

Farhat Naz, Fahad Shafiq, Tahir Hassan, Asifur Rahman, Shajahan Siraj, Shaheen Nawaz, Heyam Saad Ali, Shabnam Mahsood, Karishma Siraj, Khadija Manzar
article en

Abstract

Background Iron deficiency anemia (IDA) is a highly prevalent disorder among the pediatric population and has a significant impact on growth and health. Ferrous sulfate is commonly prescribed for the treatment of IDA; however, its efficacy in the pediatric population requires further research. Objective This study aimed to evaluate the efficacy of ferrous sulfate in improving hemoglobin (Hb) and ferritin levels in children diagnosed with IDA. Methods A quasi-experimental study was conducted involving 108 participants aged 1-8 years who were diagnosed with IDA. Participants received ferrous sulfate supplements for three months. Hemoglobin and serum ferritin levels were measured both at baseline and after three months of treatment. Results Ferrous sulfate administration resulted in a significant increase in hemoglobin levels by an average of 3.11 mg/dl and a net increase in ferritin levels by 5.9 ng/ml after 3 months of treatment. Additionally, a positive association was found between low Hb levels and underweight children<i>.</i> Conclusion Ferrous sulfate is an effective therapeutic agent for managing IDA in children, leading to significant improvements in hemoglobin and ferritin levels. Further research involving RCTs with longer follow-up periods is recommended.

CureusVol. 17(5)
Bacha Khan University (PK), Kohat University of Science and Technology (PK), Lady Reading Hospital (PK), Hayatabad Medical Complex (PK)
Openalex Percentile: Top 86%
Iron Metabolism and Disorders
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