Oxidative DNA damage and DNA repair gene variants in differentiated thyroid cancer patients treated with radioactive iodine

This is the first study to jointly evaluate urinary 8-oxoG and hOGG1/APE1 polymorphisms in Turkish DTC patients receiving RAI. No consistent associations were found with oxidative DNA damage or clinical characteristics. Larger studies are needed to validate these findings.

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Publication Details

Journal
Endocrine
Published
2025-05-26
DOI
https://doi.org/10.1007/s12020-025-04288-7
Primary Topic
DNA Repair Mechanisms
Type
article
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0.00
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article

Oxidative DNA damage and DNA repair gene variants in differentiated thyroid cancer patients treated with radioactive iodine

Evin Ademoğlu, Fevzi Necati Avsar, Tuncay Şahutoğlu, Semra Doğru‐Abbasoğlu
Endocrine
DNA Repair Mechanisms
article

Oxidative DNA damage and DNA repair gene variants in differentiated thyroid cancer patients treated with radioactive iodine

Evin Ademoğlu, Fevzi Necati Avsar, Tuncay Şahutoğlu, Semra Doğru‐Abbasoğlu
article en

Abstract

This is the first study to jointly evaluate urinary 8-oxoG and hOGG1/APE1 polymorphisms in Turkish DTC patients receiving RAI. No consistent associations were found with oxidative DNA damage or clinical characteristics. Larger studies are needed to validate these findings.

EndocrineVol. 89(3)
Şanlıurfa Mehmet Akif İnan Eğitim ve Araştırma Hastanesi (TR), Sağlık Bilimleri Üniversitesi (TR), Istanbul University (TR)
Good health and well-being
Openalex Percentile: Top 90%
DNA Repair Mechanisms
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