An integrated approach to the treatment of acute inflammatory diseases of the larynx

Acute inflammatory diseases of the larynx are a group of the most common diseases among both adults and children, which are caused by a number of infectious and non-infectious factors. Despite the fact that most cases of acute inflammatory diseases of the larynx are viral in nature, treatment often involves unjustified prescribing of systemic antibiotics, which contributes to the development of the problem of antibiotic resistance. The purpose of this article is to conduct an analytical review of existing methods of complex treatment for acute inflammatory diseases of the larynx and new drugs of complex action, the use of which can reduce the need for irrational antibiotic therapy. Immunostimulants boost the innate and acquired immunity, act on both cellular and humoral immunity, activate nonspecific defences and help to develop specific immune response. Bacterial lysates, mixtures of antigens derived from inactivated bacteria representing the most common pathogens, are the most effective group of immunostimulants. The administration of combination immunostimulants may help in enhancing a relief of symptoms of acute inflammatory diseases of the larynx, improve recovery times for patients, reduce systemic antibiotics prescribing rates and decrease the incidence of acute respiratory infections by expanding body’s resistance to various respiratory disease agents.