Biomarker-based evaluation of aflatoxin B1 exposure in cattle
The consistent detection of AFB1-albumin and AFB1-DNA adducts in cattle, irrespective of detectable aflatoxin levels in feed, underscores the limitations of traditional feed analysis for monitoring chronic exposure. The novel synthesis and robust detection of AFB1-FAPy DNA adducts further enhance the reliability of these biomarkers. These biomarkers are minimally invasive, sensitive, and valuable for chronic aflatoxin exposure assessment, aiding proactive management strategies to safeguard animal health and public food safety.
Authors
- Umaya Suganthi Rajendran (ORCID: https://orcid.org/0000-0002-7710-6271)
- Poobitha Subbarayan
- A.W. Lakkawar (ORCID: https://orcid.org/0009-0005-2520-9841)
- Uma Sambath (ORCID: https://orcid.org/0000-0002-5641-5059)
- J. Thanislass
- V. D. Padmanaban (ORCID: https://orcid.org/0009-0001-2661-8621)
- Raja Kumar (ORCID: https://orcid.org/0000-0001-8843-1478)
- Madhavan Nair (ORCID: https://orcid.org/0000-0002-7882-9121)
- Priyadharshini Ponnusamy (ORCID: https://orcid.org/0009-0004-4354-3088)
Institutions
- Rajiv Gandhi University of Health Sciences (IN)
- National Institute of Animal Nutrition and Physiology (IN)
Publication Details
- Journal
- Veterinary World
- Published
- 2025-05-01
- DOI
- https://doi.org/10.14202/vetworld.2025.1297-1305
- Primary Topic
- Mycotoxins in Agriculture and Food
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Indian Council of Agricultural Research
- National Institute of Animal Nutrition and Physiology