Early Elevation of Monocytic-to-Polymorphonuclear Myeloid-Derived Suppressor Cells Ratio in Critical Illness is Associated with Favorable Clinical Outcomes
Elevated levels of M-MDSCs in the early stages of critical illness may exert protective effects. The ratio of M-MDSCs/PMN-MDSCs demonstrates predictive value for 28-day mortality, positioning it as a potential biomarker for prognostic assessment, but further multicenter studies are still needed to validate it.
Authors
- Heling Zhao (ORCID: https://orcid.org/0000-0002-0395-9992)
- Ge Chen (ORCID: https://orcid.org/0000-0002-0501-372X)
- Ze Zhang (ORCID: https://orcid.org/0000-0002-5336-8875)
- Lijing Jia (ORCID: https://orcid.org/0000-0001-6329-0269)
- Ling Long (ORCID: https://orcid.org/0000-0002-5786-0189)
- Zhiyang Zhang (ORCID: https://orcid.org/0009-0004-4057-7098)
- Huawei Wang (ORCID: https://orcid.org/0009-0004-3677-9199)
Institutions
- Hebei General Hospital (CN)
Publication Details
- Journal
- Journal of Inflammation Research
- Published
- 2025-05-01
- DOI
- https://doi.org/10.2147/jir.s517333
- Citations
- 2
- Primary Topic
- Immune cells in cancer
- Type
- article
- Field-Weighted Citation Impact
- 1.59