Phytochemical Analysis and Antioxidant Activity Assessment of Croton linearifolius Stem Extracts
Croton linearifolius is a species with promising medicinal potential. This study investigated the antioxidant activity, total phenolic and flavonoid contents, and conducted chemical prospecting of its ethanolic stem extract and fractions. The extract was obtained by exhaustive percolation with 70% hydroethanolic solution, followed by liquid-liquid partitioning using hexane, dichloromethane, and ethyl acetate. In vitro tests were used for chemical analysis, and antioxidant activity was evaluated by DPPH and FRAP methods. The ethyl acetate fraction showed the highest antioxidant activity (80.62% in DPPH), with elevated phenolic and flavonoid levels, indicating potential for herbal medicine development.
Authors
- Simone Andrade Gualberto (ORCID: https://orcid.org/0000-0002-1753-002X)
- Matheus Andrade Rocha Costa (ORCID: https://orcid.org/0000-0003-0194-3310)
- Marcel Mark da Silva Passos (ORCID: https://orcid.org/0000-0002-2832-9882)
- Cleia Teixeira Santos de Franca (ORCID: https://orcid.org/0000-0002-5566-1469)
- Esaul Lucas Oliveira (ORCID: https://orcid.org/0009-0008-8594-7637)
Institutions
- Universidade Federal de Pernambuco (BR)
- Southwest Bahia State University (BR)
- Universidade Federal de Catalão (BR)
Publication Details
- Journal
- Semina Ciências Exatas e Tecnológicas
- Published
- 2025-04-09
- DOI
- https://doi.org/10.5433/1679-0375.2025.v46.50875
- Primary Topic
- Phytochemistry and Bioactivity Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Conselho Nacional de Desenvolvimento Científico e Tecnológico
- Universidade Estadual do Sudoeste da Bahia