Associations of waist circumference to height ratio and body mass index through childhood and adolescence on blood pressure and risk of young adult hepatic steatosis: a cohort study
Excess adiposity or weight in early life, continuing to adulthood, elevates hepatic steatosis risk and associates with increased SBP in adulthood. These findings highlight the impact of youth adiposity and weight on later health outcomes. The strong association of WHtR and hepatic steatosis risk suggests it may be an alternative to BMI, with potential use in paediatric risk stratification.
Authors
- Sam Leary (ORCID: https://orcid.org/0000-0002-1706-0689)
- Julian Hamilton‐Shield (ORCID: https://orcid.org/0000-0003-2601-7575)
- Kushala Abeysekera (ORCID: https://orcid.org/0000-0001-7301-8250)
- Nicholas J. Timpson (ORCID: https://orcid.org/0000-0002-7141-9189)
- Sumona Mandal (ORCID: https://orcid.org/0000-0002-6031-8091)
Institutions
- University Of Bristol Dental Hospital (GB)
- University Hospitals Bristol NHS Foundation Trust (GB)
- Bristol Royal Infirmary (GB)
- University of Bristol (GB)
- NIHR Bristol Biomedical Research Centre (GB)
- MRC Epidemiology Unit (GB)
- University Hospitals Bristol and Weston NHS Foundation Trust (GB)
Publication Details
- Journal
- Archives of Disease in Childhood
- Published
- 2025-05-26
- DOI
- https://doi.org/10.1136/archdischild-2024-328140
- Citations
- 3
- Primary Topic
- Birth, Development, and Health
- Type
- article
- Field-Weighted Citation Impact
- 10.48
Funders
- Wellcome Trust
- NIHR Bristol Biomedical Research Centre
- University of Bristol
- Medical Research Council