Pan-cancer analysis of homologous recombination deficiency and homologous recombination repair–associated gene alterations in solid tumors from a large Asian cohort
This is the largest pan-cancer HRD study in an Asian population, providing insights for future HRD testing and targeted therapy.
Authors
- Zhou Zhang
- Yan Huang (ORCID: https://orcid.org/0000-0001-5965-5739)
- Runsi Yao
- Ting Hou (ORCID: https://orcid.org/0000-0003-1733-646X)
- Xiaojun Chen (ORCID: https://orcid.org/0000-0002-5493-1500)
- Cheng‐Lin Liu (ORCID: https://orcid.org/0000-0001-9032-2991)
- Lili Ren (ORCID: https://orcid.org/0000-0001-6423-9625)
- Fei Zhao
Institutions
- Burning Rock Biotech (China) (CN)
- Affiliated Hospital of Hebei University (CN)
Publication Details
- Journal
- BMC Cancer
- Published
- 2025-05-26
- DOI
- https://doi.org/10.1186/s12885-025-14267-w
- Citations
- 4
- Primary Topic
- PARP inhibition in cancer therapy
- Type
- article
- Field-Weighted Citation Impact
- 4.18