The efficacy of moxibustion on the pressure pain threshold and substance P / leukotriene B4 contents in serum to patients with rheumatoid arthritis
Moxibustion combined with conventional western medicine can significantly improve PPTs in affected joints of RA patients, alleviate clinical symptoms, and reduce disease activity. The potential mechanism may be related to the down-regulation of SP and LTB4 levels and the reduction of the release of inflammatory factors Il-1β and TNF-α by moxibustion. The lack of double-blinding is a limitation of our study, which we plan to avoid by establishing a sham moxibustion group in the subsequent trials.
Authors
- Xue Wang (ORCID: https://orcid.org/0000-0002-8205-7240)
- Yi Yang (ORCID: https://orcid.org/0000-0001-6657-4814)
- Ping Wu (ORCID: https://orcid.org/0000-0003-4062-9447)
- Siyu Tao (ORCID: https://orcid.org/0000-0002-5092-1743)
- Nannan Jiang
- Yuan Li (ORCID: https://orcid.org/0000-0003-1694-5108)
- Jie Tang (ORCID: https://orcid.org/0000-0002-6219-8177)
Institutions
- Chengdu University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Complementary Therapies in Medicine
- Published
- 2025-05-26
- DOI
- https://doi.org/10.1016/j.ctim.2025.103187
- Citations
- 2
- Primary Topic
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Type
- article
- Field-Weighted Citation Impact
- 2.94
Funders
- National Natural Science Foundation of China
- Education Department of Sichuan Province