Genomic landscape of paired primary and peritoneal metastatic lesions in gastric cancer highlights evolutionary dynamics and mutational drivers

Our study elucidates clonal evolution in gastric cancer peritoneal metastasis, identifies mutational drivers, and highlights potential therapeutic targets. These findings provide valuable insights for developing precise treatment strategies for gastric cancer patients with peritoneal metastasis.

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Publication Details

Journal
Journal of Advanced Research
Published
2025-05-26
DOI
https://doi.org/10.1016/j.jare.2025.05.043
Citations
3
Primary Topic
Gastric Cancer Management and Outcomes
Type
article
Field-Weighted Citation Impact
4.56

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article

Genomic landscape of paired primary and peritoneal metastatic lesions in gastric cancer highlights evolutionary dynamics and mutational drivers

Jianyuan Zhou, Xinyu Song, Ying Sun, Chunyan Ji et al.
3 citations
Journal of Advanced Research
Gastric Cancer Management and Outcomes
4.56
article

Genomic landscape of paired primary and peritoneal metastatic lesions in gastric cancer highlights evolutionary dynamics and mutational drivers

Jianyuan Zhou, Xinyu Song, Ying Sun, Chunyan Ji, Xuanyu Zhou, Zhaodi Nan, Fan Jiang, Xuehui Wu, Wenli Zhao, Song Li, Liping Dou, Lian Liu, Huan Wang, Di Zhang, Weiwei Zhang, Qian Xu, Xin Dai, Jin Jiao, Jiahui Chu, Xiangyong Liu, Shuhan Li, Qiao Hu, Qian Yang, Shulun Nie, Shuang Wang
article en
3 citations

Abstract

Our study elucidates clonal evolution in gastric cancer peritoneal metastasis, identifies mutational drivers, and highlights potential therapeutic targets. These findings provide valuable insights for developing precise treatment strategies for gastric cancer patients with peritoneal metastasis.

Journal of Advanced ResearchVol. 81
Qingdao University (CN), Shandong University of Traditional Chinese Medicine (CN), Shandong Provincial Hospital (CN), Affiliated Hospital of Qingdao University (CN), Qilu Hospital of Shandong University (CN), University of Nebraska Medical Center (US)
National Natural Science Foundation of China, Natural Science Foundation of Shandong Province
Good health and well-being
Openalex Percentile: Top 6%
Gastric Cancer Management and Outcomes
4.56
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