[18F]-FLT-PET to evaluate how the sequencing of chemotherapies impacts the efficacy of combination treatment in mouse models of triple-negative breast cancer
Our study highlights the immune system's critical role in enhancing chemotherapy's efficacy. It provides compelling evidence that imaging can guide the sequencing of therapies by tracking changes in cellular proliferation and the heterogeneity of tumor response. This approach underscores the potential to refine treatment strategies for improved therapeutic outcomes.
Authors
- Patrick N. Song (ORCID: https://orcid.org/0000-0002-1545-0886)
- Adriana V. F. Massicano (ORCID: https://orcid.org/0000-0002-6666-1317)
- Sharon Samuel (ORCID: https://orcid.org/0000-0002-5211-0661)
- Janet P Moye (ORCID: https://orcid.org/0009-0007-1588-8267)
- Shannon E. Lynch (ORCID: https://orcid.org/0000-0002-0325-2823)
- Yun Lü (ORCID: https://orcid.org/0000-0002-4785-3401)
- Anna G. Sorace (ORCID: https://orcid.org/0000-0002-3640-3966)
- Carlos Gallegos (ORCID: https://orcid.org/0000-0002-8336-2677)
Institutions
- University of Alabama at Birmingham Hospital (US)
- University of Alabama at Birmingham (US)
Publication Details
- Journal
- Neoplasia
- Published
- 2025-05-26
- DOI
- https://doi.org/10.1016/j.neo.2025.101184
- Citations
- 1
- Primary Topic
- Cancer Genomics and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 0.94