A head-to-head comparison of the validity and predictive ability for health outcomes of diagnosis versus medication-based comorbidity indices
Rx-Risk demonstrated slightly superior validity and predictive ability for HRQoL and healthcare utilization, making it a promising option for studies focused on these outcomes. However, limitations regarding functional and cognitive impairment suggest alternative instruments are needed.
Authors
- Anika Rädke (ORCID: https://orcid.org/0000-0003-0634-8756)
- M Pfaff (ORCID: https://orcid.org/0009-0000-5239-1769)
- Fabian Kleinke (ORCID: https://orcid.org/0000-0003-0092-7263)
- Maresa Buchholz (ORCID: https://orcid.org/0000-0002-4486-8632)
- Neeltje van den Berg (ORCID: https://orcid.org/0000-0001-6965-0544)
- Annelie Scharf (ORCID: https://orcid.org/0000-0002-0910-088X)
- Moritz Platen (ORCID: https://orcid.org/0000-0001-6438-7230)
- Wolfgang Hoffmann (ORCID: https://orcid.org/0000-0002-6359-8797)
- Arif Iskandar
- Bernhard Michalowsky
Institutions
- Universitätsmedizin Greifswald (DE)
- German Center for Neurodegenerative Diseases (DE)
Publication Details
- Journal
- Aging Clinical and Experimental Research
- Published
- 2025-05-27
- DOI
- https://doi.org/10.1007/s40520-025-03073-w
- Primary Topic
- Chronic Disease Management Strategies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Gemeinsame Bundesausschuss