Deep sequencing analysis of hepatitis B virus in patients with incomplete response to tenofovir alafenamide fumarate treatment

The deep sequencing analysis of HBV DNA and RNA and comparing the detection rates of mutations were useful for estimating responsible mutations for TAF-incomplete responses. Such analysis is needed to evaluate the association between mutations that emerge during TAF treatment and incomplete responses to TAF.

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Publication Details

Journal
World Journal of Hepatology
Published
2025-05-27
DOI
https://doi.org/10.4254/wjh.v17.i5.104519
Primary Topic
Hepatitis B Virus Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Deep sequencing analysis of hepatitis B virus in patients with incomplete response to tenofovir alafenamide fumarate treatment

Takanobu Kato, Masumichi Saito, N. Yamada, Masanori Isogawa et al.
World Journal of Hepatology
Hepatitis B Virus Studies
article

Deep sequencing analysis of hepatitis B virus in patients with incomplete response to tenofovir alafenamide fumarate treatment

Takanobu Kato, Masumichi Saito, N. Yamada, Masanori Isogawa, Kiyomi Yasuda, H. Igarashi, Asako Murayama, Michihiro Suzuki
article en

Abstract

The deep sequencing analysis of HBV DNA and RNA and comparing the detection rates of mutations were useful for estimating responsible mutations for TAF-incomplete responses. Such analysis is needed to evaluate the association between mutations that emerge during TAF treatment and incomplete responses to TAF.

World Journal of HepatologyVol. 17(5)
National Institute of Infectious Diseases (JP)
Good health and well-being
Openalex Percentile: Top 83%
Hepatitis B Virus Studies
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