The decay-accelerating factor (CD55) in acute leukemia patients and its query implication in cancer pathogenesis
CD55 was significantly downregulated in acute leukemia. However, its in vitro silencing showed significant reduction in cell viability, giving it a dual opposing role in cancer.
Authors
- Mohamed A. Abd El Aziz (ORCID: https://orcid.org/0000-0003-4477-0114)
- Hisham Abdelaziz
- Samar Kassem
- Mona S. Abdellateif (ORCID: https://orcid.org/0000-0002-5510-4435)
- Noha Hassan (ORCID: https://orcid.org/0000-0003-4965-3654)
- Noha E. Farag (ORCID: https://orcid.org/0009-0003-3513-608X)
- Ghada Elnaggar (ORCID: https://orcid.org/0000-0001-6216-6549)
- Perihan Mohamed
- Khaled Abo-Aisha
Institutions
- Cairo University (EG)
- October 6 University (EG)
- German University in Cairo (EG)
Publication Details
- Journal
- Journal of the Egyptian National Cancer Institute
- Published
- 2025-05-26
- DOI
- https://doi.org/10.1186/s43046-025-00299-7
- Primary Topic
- Complement system in diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00