Preliminary exploration of PSMA CAR-T combined with GD2 CAR-T for the treatment of refractory/relapsed gliomas
Combined PSMA CAR-T and GD2 CAR-T cell therapy demonstrated significant efficacy and good tolerability in the treatment of refractory/relapsed gliomas, without severe adverse reactions.
Authors
- Yang Xu (ORCID: https://orcid.org/0000-0003-1468-2703)
- Zhengfeng Lu (ORCID: https://orcid.org/0000-0001-9644-6039)
- Lung‐Ji Chang (ORCID: https://orcid.org/0000-0003-2395-5216)
- Rui Jia
- Cheng‐Wei Tom Chang (ORCID: https://orcid.org/0000-0002-8978-4520)
- Jiang Gu (ORCID: https://orcid.org/0000-0002-0706-8329)
- Huajuan Ma
- Ge Zhang (ORCID: https://orcid.org/0000-0002-1663-8979)
- Jiasheng Li (ORCID: https://orcid.org/0000-0002-3378-3123)
- Wei Chen (ORCID: https://orcid.org/0000-0002-8159-5514)
- Qichun Cai
- Haijun Wen
- Junjie Xie (ORCID: https://orcid.org/0009-0003-4487-2791)
Institutions
- Sun Yat-sen University (CN)
- Panyu Hospital of Chinese Medicine (CN)
- Panyu District Central Hospital (CN)
- Shenzhen Genoimmune Medical Institute (CN)
Publication Details
- Journal
- Journal of Translational Medicine
- Published
- 2025-05-26
- DOI
- https://doi.org/10.1186/s12967-025-06523-1
- Citations
- 4
- Primary Topic
- CAR-T cell therapy research
- Type
- article
- Field-Weighted Citation Impact
- 4.18
Funders
- Basic and Applied Basic Research Foundation of Guangdong Province