Revascularization strategies in acute stroke with tandem occlusions: The Impact of Dissection vs. Atherosclerotic etiology on Clinical Outcomes

This study on tandem occlusions found that patients with carotid dissection experienced better clinical outcomes than those with atherosclerotic carotid disease, despite a higher rate of stent reocclusion. However, multivariate analysis indicated that the underlying etiology was not an independent predictor of outcome; instead, patient age and initial stroke severity were more influential factors. Given the increased risk of reocclusion, patients with carotid dissection may benefit from a more individualized antithrombotic strategy to maintain stent patency.

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Publication Details

Journal
Journal of Stroke and Cerebrovascular Diseases
Published
2025-05-26
DOI
https://doi.org/10.1016/j.jstrokecerebrovasdis.2025.108362
Primary Topic
Acute Ischemic Stroke Management
Type
article
Field-Weighted Citation Impact
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article

Revascularization strategies in acute stroke with tandem occlusions: The Impact of Dissection vs. Atherosclerotic etiology on Clinical Outcomes

Miklós Krepuska, Tilman B. Schubert, Patrick Thurner, Andreas R. Luft et al.
Journal of Stroke and Cerebrovascular Diseases
Acute Ischemic Stroke Management
article

Revascularization strategies in acute stroke with tandem occlusions: The Impact of Dissection vs. Atherosclerotic etiology on Clinical Outcomes

Miklós Krepuska, Tilman B. Schubert, Patrick Thurner, Andreas R. Luft, Zsolt Kulcsár, Jawid Madjidyar, Christoph Globas, Susanne Wegener, Mara Z. Thut, Gregory Howaldt
article en

Abstract

This study on tandem occlusions found that patients with carotid dissection experienced better clinical outcomes than those with atherosclerotic carotid disease, despite a higher rate of stent reocclusion. However, multivariate analysis indicated that the underlying etiology was not an independent predictor of outcome; instead, patient age and initial stroke severity were more influential factors. Given the increased risk of reocclusion, patients with carotid dissection may benefit from a more individualized antithrombotic strategy to maintain stent patency.

Journal of Stroke and Cerebrovascular DiseasesVol. 34(8)
University of Zurich (CH), Laboratory for Biomedical Neurosciences (CH), University Hospital of Zurich (CH)
Good health and well-being
Openalex Percentile: Top 83%
Acute Ischemic Stroke Management
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Revascularization strategies in acute stroke with tandem occlusions: The Impact of Dissection vs. Atherosclerotic etiology on Clinical Outcomes — Miklós Krepuska, Tilman B. Schubert, et al. · Journal of Stroke and Cerebrovascular Diseases (2025) | TGRS Research Map | TGRS