<i>ShiNyP</i>: Unlocking SNP-Based Population Genetics—AI-Assisted Platform for Rapid and Interactive Visual Exploration

Efficient and accessible analysis of genome-wide single nucleotide polymorphism data is vital for advancing molecular biology, evolutionary genetics, and breeding research. However, current analytical pipelines are often fragmented and require command-line expertise, limiting accessibility for many researchers. Here, we present ShiNyP, an interactive R/Shiny platform that integrates all popular single nucleotide polymorphism analysis modules within a single and intuitive user interface, supporting the entire workflow from data import and quality control to population structure inference, diversity analysis, selective scan, and core collection. ShiNyP accommodates datasets from haploid, diploid, and polyploid species and automates the generation of over 70 publication-ready visualizations and summary tables. A distinctive feature is its automated report module, which employs generative AI to deliver structured, interpretable narratives of complex statistical results. Performance benchmarks demonstrate that ShiNyP efficiently processes large-scale datasets on standard hardware. The ShiNyP platform is freely available at https://github.com/TeddYenn/ShiNyP, providing an efficient, reproducible, and user-friendly solution for population genomics research.

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Publication Details

Journal
Molecular Biology and Evolution
Published
2025-05-26
DOI
https://doi.org/10.1093/molbev/msaf117
Citations
1
Primary Topic
Genomics and Phylogenetic Studies
Type
article
Field-Weighted Citation Impact
0.81

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article

ShiNyP: Unlocking SNP-Based Population Genetics—AI-Assisted Platform for Rapid and Interactive Visual Exploration

Endang M. Septiningsih, Pei-Hsiu Kao, Yen-Hsiang Huang, Lingyu Chen et al.
1 citations
Molecular Biology and Evolution
Genomics and Phylogenetic Studies
0.81
article

ShiNyP: Unlocking SNP-Based Population Genetics—AI-Assisted Platform for Rapid and Interactive Visual Exploration

Endang M. Septiningsih, Pei-Hsiu Kao, Yen-Hsiang Huang, Lingyu Chen, Chung‐Feng Kao
article en
1 citations

Abstract

Efficient and accessible analysis of genome-wide single nucleotide polymorphism data is vital for advancing molecular biology, evolutionary genetics, and breeding research. However, current analytical pipelines are often fragmented and require command-line expertise, limiting accessibility for many researchers. Here, we present ShiNyP, an interactive R/Shiny platform that integrates all popular single nucleotide polymorphism analysis modules within a single and intuitive user interface, supporting the entire workflow from data import and quality control to population structure inference, diversity analysis, selective scan, and core collection. ShiNyP accommodates datasets from haploid, diploid, and polyploid species and automates the generation of over 70 publication-ready visualizations and summary tables. A distinctive feature is its automated report module, which employs generative AI to deliver structured, interpretable narratives of complex statistical results. Performance benchmarks demonstrate that ShiNyP efficiently processes large-scale datasets on standard hardware. The ShiNyP platform is freely available at https://github.com/TeddYenn/ShiNyP, providing an efficient, reproducible, and user-friendly solution for population genomics research.

Molecular Biology and EvolutionVol. 42(6)
National Chung Hsing University (TW), The University of Melbourne (AU), Texas A&M University (US)
Academia Sinica, National Science and Technology Council
Openalex Percentile: Top 28%
Genomics and Phylogenetic Studies
0.81
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<i>ShiNyP</i>: Unlocking SNP-Based Population Genetics—AI-Assisted Platform for Rapid and Interactive Visual Exploration — Endang M. Septiningsih, Pei-Hsiu Kao, et al. · Molecular Biology and Evolution (2025) | TGRS Research Map | TGRS