Obefazimod in patients with moderate-to-severely active ulcerative colitis: efficacy and safety analysis from the 96-week open-label maintenance phase 2b study

A phase 2b, open-label, efficacy and safety study of ABX464 as maintenance therapy in patients with moderate-to-severe UC. NCT04023396.

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Publication Details

Journal
Journal of Crohn s and Colitis
Published
2025-05-01
DOI
https://doi.org/10.1093/ecco-jcc/jjaf074
Citations
9
Primary Topic
Inflammatory Bowel Disease
Type
article
Field-Weighted Citation Impact
16.36
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article

Obefazimod in patients with moderate-to-severely active ulcerative colitis: efficacy and safety analysis from the 96-week open-label maintenance phase 2b study

Severine A.R.A. Vermeire, Marla C. Dubinsky, Julien Santo, Parambir S. Dulai et al.
9 citations
Journal of Crohn s and Colitis
Inflammatory Bowel Disease
16.36
article

Obefazimod in patients with moderate-to-severely active ulcerative colitis: efficacy and safety analysis from the 96-week open-label maintenance phase 2b study

Severine A.R.A. Vermeire, Marla C. Dubinsky, Julien Santo, Parambir S. Dulai, Didier Scherrer, Britta Siegmund, K Shan, Paul Gineste, Tadakazu Hisamatsu, Josianne Nitcheu, Herbert Tilg, Silvio Danese, Christopher J. Rabbat, Aurélien Flatres, Laurent Peyrin-Biroulet, Bruce E. Sands
article en
9 citations

Abstract

A phase 2b, open-label, efficacy and safety study of ABX464 as maintenance therapy in patients with moderate-to-severe UC. NCT04023396.

Journal of Crohn s and ColitisVol. 19(5)
Northwestern University (US), Innsbruck Medical University (AT), Inserm (FR), Universität Innsbruck (AT), Humboldt-Universität zu Berlin (DE), Mount Sinai Hospital (US), IRCCS Ospedale San Raffaele (IT), Kyorin University Hospital (JP), Abivax (France) (FR), Nutrition-Génétique et Exposition aux Risques Environnementaux (FR), Freie Universität Berlin (DE), Charité - Universitätsmedizin Berlin (DE), Icahn School of Medicine at Mount Sinai (US), KU Leuven (BE)
Good health and well-being
Openalex Percentile: Top 1%
Inflammatory Bowel Disease
16.36
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Obefazimod in patients with moderate-to-severely active ulcerative colitis: efficacy and safety analysis from the 96-week open-label maintenance phase 2b study — Severine A.R.A. Vermeire, Marla C. Dubinsky, et al. · Journal of Crohn s and Colitis (2025) | TGRS Research Map | TGRS