Myeloperoxidase Enzyme Activity in Feces Reflects Endoscopic Severity in Inflammatory Bowel Disease
Myeloperoxidase is active in IBD and its enzyme activity is a reliable marker of IBD endoscopic inflammation. Our results with the CM-S fMPOa assay demonstrate the potential for an immediate and accurate measure of fMPO enzyme activity as a robust, low-cost test for IBD activity. Myeloperoxidase may contribute to tissue damage in IBD.
Authors
- Grace M Borichevsky (ORCID: https://orcid.org/0000-0002-7060-7743)
- Chris Frampton (ORCID: https://orcid.org/0000-0003-0603-5661)
- Louisa V. Ashby (ORCID: https://orcid.org/0000-0001-8247-096X)
- Akhilesh Swaminathan (ORCID: https://orcid.org/0000-0003-1954-844X)
- Richard B. Gearry (ORCID: https://orcid.org/0000-0002-2298-5141)
- Anthony J. Kettle
- Andrew S. Day (ORCID: https://orcid.org/0000-0003-2290-7386)
- Teagan S. Edwards
- B R Smith (ORCID: https://orcid.org/0009-0007-7875-5066)
Institutions
- Christchurch Hospital (NZ)
- Christ University (IN)
- University of Otago (NZ)
Publication Details
- Journal
- Inflammatory Bowel Diseases
- Published
- 2025-05-24
- DOI
- https://doi.org/10.1093/ibd/izaf109
- Citations
- 6
- Primary Topic
- Inflammatory Bowel Disease
- Type
- article
- Field-Weighted Citation Impact
- 10.90