Correlation study of LINC02609 and SNHG17 as prognostic biomarkers of kidney renal clear cell carcinoma and therapeutic sensitivity based on public data and In Vitro analysis
The candidate biomarker LINC02609 regulates the progression of renal cell carcinoma through the MAPK signaling pathway. The risk model constructed using LINC02609 and SNHG17 was significantly correlated with multiple immunotherapy-related signatures, suggesting that it might be used for the determination of immunotherapy options in KIRC.
Authors
- Chaoqun Xing
- Xiao‐Liang Xing (ORCID: https://orcid.org/0000-0003-3075-3102)
- Y.X. Li (ORCID: https://orcid.org/0000-0002-6564-2106)
- Fan Yao
- Zhiyong Yao (ORCID: https://orcid.org/0000-0003-4663-2516)
- Ti Zhang (ORCID: https://orcid.org/0000-0002-0420-644X)
- Weiwei Zou
Institutions
- Huaihua University (CN)
- Xuzhou Medical College (CN)
- First Affiliated Hospital of Hunan University of Traditional Chinese Medicine (CN)
- Second People’s Hospital of Huai’an (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-05-26
- DOI
- https://doi.org/10.3389/fimmu.2025.1592474
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Hunan Provincial Science and Technology Department