Morinda officinalis oligosaccharides attenuate mitochondria-associated ferroptosis via the NOX4/mitoGPX4 pathway in myocardial ischemia‒reperfusion injury
These results indicate the beneficial effects of MOO on myocardial I/R injury by suppressing oxidative stress and mitochondria-associated ferroptosis through NOX4/mitoGPX4 pathway.
Authors
- Bo Guan (ORCID: https://orcid.org/0000-0002-0824-3256)
- Wenjun Mao
- Qi Song
- Yih‐Leong Chang (ORCID: https://orcid.org/0000-0001-5309-0554)
- Chao Chen
- Lin Chen (ORCID: https://orcid.org/0000-0002-7145-7564)
- Yan Zhang (ORCID: https://orcid.org/0000-0003-2146-1052)
- Wenting Chen (ORCID: https://orcid.org/0000-0003-4230-1189)
- Wei Li (ORCID: https://orcid.org/0000-0001-5602-2709)
- Yuan Tian (ORCID: https://orcid.org/0000-0002-1856-0693)
- Yan Xiao-pei
- Li Su (ORCID: https://orcid.org/0000-0002-4556-6863)
- Yuqiong Chen (ORCID: https://orcid.org/0000-0001-7592-5989)
Institutions
- Xuzhou Medical College (CN)
- Nantong University (CN)
- Fudan University (CN)
- Jinshan Hospital of Fudan University (CN)
- Suzhou Municipal Hospital (CN)
- The Affiliated Taizhou People's Hospital of Nanjing Medical University (CN)
- Zhongshan Hospital (CN)
- Xuzhou Central Hospital (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- Frontiers in Cell and Developmental Biology
- Published
- 2025-05-26
- DOI
- https://doi.org/10.3389/fcell.2025.1605513
- Citations
- 4
- Primary Topic
- Inflammation biomarkers and pathways
- Type
- article
- Field-Weighted Citation Impact
- 3.19