Association between heavy metal exposure and heart failure incidence and mortality: insights from NHANES data (2003–2018)
These findings underscore cadmium's role as a risk factor and the paradoxical effects of mercury and arsenic: low to moderate concentrations of Hg/As may reduce HF risk through indirect pathways (e.g., reduced CHD/OMI for Hg) or direct cardioprotective mechanisms (for As), yet arsenic's association with mortality highlights its long-term cardiovascular toxicity. Findings advocate for preventive strategies targeting metal exposure and further research integrating cumulative biomarkers.
Authors
- Shengfang Wang
- Yang Bai (ORCID: https://orcid.org/0000-0001-6751-3896)
- Guanzhen Lai
- Yuhao Liu (ORCID: https://orcid.org/0000-0002-0447-6677)
- Xiaohu Wang (ORCID: https://orcid.org/0000-0002-0018-1847)
- Zebin Lin
- Jianmin Tang (ORCID: https://orcid.org/0000-0002-9257-1411)
- X B Di
- Yongqi Dong
- Yipin Zhao
Institutions
- Second Affiliated Hospital of Zhengzhou University (CN)
- Zhongshan Hospital of Xiamen University (CN)
- Second Affiliated Hospital of Xi'an Jiaotong University (CN)
- Henan Provincial People's Hospital (CN)
Publication Details
- Journal
- BMC Public Health
- Published
- 2025-05-26
- DOI
- https://doi.org/10.1186/s12889-025-23177-2
- Citations
- 4
- Primary Topic
- Heavy Metal Exposure and Toxicity
- Type
- article
- Field-Weighted Citation Impact
- 4.80