Peripheral skin cooling during gravitational challenges in parabolic flight – experimental protocol, implementation, and case study of the CoolFly experiment
This proof-of-concept study demonstrates that peripheral cooling is feasible during parabolic flight and may attenuate cardiovascular responses, as indicated by reduced heart rate and blood pressure fluctuations. These preliminary findings support further controlled studies to assess PC as a non-invasive countermeasure to changes in gravitation.
Authors
- Niklas Pilz (ORCID: https://orcid.org/0000-0002-1195-8359)
- Tomas L. Bothe (ORCID: https://orcid.org/0000-0001-7569-4527)
- Michael Nordine (ORCID: https://orcid.org/0000-0002-5510-0776)
- Renana Bruckstein
- Oliver Opatz (ORCID: https://orcid.org/0000-0003-4746-9343)
- V. Heinz (ORCID: https://orcid.org/0009-0002-5363-793X)
- Andreas Reinhold Patzak (ORCID: https://orcid.org/0000-0002-1088-6875)
- Hanns‐Christian Gunga (ORCID: https://orcid.org/0000-0002-0145-179X)
- Leon Fesseler (ORCID: https://orcid.org/0009-0001-3420-5915)
Institutions
- Goethe University Frankfurt (DE)
- Medizinische Hochschule Hannover (DE)
- University Hospital Frankfurt (DE)
- Berlin Institute of Health at Charité - Universitätsmedizin Berlin (DE)
- Charité - Universitätsmedizin Berlin (DE)
Publication Details
- Journal
- Frontiers in Physiology
- Published
- 2025-05-26
- DOI
- https://doi.org/10.3389/fphys.2025.1477311
- Primary Topic
- Spaceflight effects on biology
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Deutsches Zentrum für Luft- und Raumfahrt